Resuscitation
Umbrella treatment of burn shock and the first 48 hours of resuscitation. Bounded by under-resuscitation (acute kidney injury, shock-related death) and over-resuscitation (fluid creep, abdominal and orbital compartment syndromes). Spans burn-shock physiology, vascular access…
- Abdominal compartment syndrome in burn resuscitation
Abdominal compartment syndrome (ACS) is a sustained intra-abdominal pressure above 20 mmHg with new organ dysfunction, arising in severely burned patients as a secondary complication of large-volume…
- Burn shock pathophysiology
Burn shock is the early hypovolemic-distributive shock state after major thermal injury. A generalized rise in microvascular permeability drives plasma loss and edema in burned and unburned tissue…
- Crystalloid versus colloid and albumin choice in burn resuscitation
Lactated Ringer's crystalloid is the resuscitation baseline for major burns, but colloids reduce total fluid volume. Colloid trials show lower 24-hour volumes and edema, while older meta-analyses…
- High-dose ascorbic acid burn resuscitation
High-dose ascorbic acid (vitamin C) is an antioxidant adjunct to crystalloid resuscitation in large burns. By scavenging oxygen free radicals it reduces microvascular leak; the most-cited human trial…
- Parkland / Baxter Formula and Fluid Volume Titration
The Parkland (Baxter) formula estimates the first-24-hour crystalloid volume for major burns as 4 mL/kg/%TBSA lactated Ringer's, half in the first 8 hours. It is a starting estimate, not a fixed…
Management of plasma volume loss after thermal injury. The clinical frame is bounded by under-resuscitation (shock, acute kidney injury, death) and over-resuscitation ("fluid creep," pulmonary edema, compartment syndromes). Contemporary practice combines Parkland or modified…
- Hypertonic saline resuscitationin editorial review
- Albumin resuscitation in burns
Albumin is the most widely used colloid in burn resuscitation. The 2024 ABA clinical practice guideline supports its use, especially in larger burns, to reduce resuscitation volumes and improve urine…
- Fresh frozen plasma resuscitation in burns
Fresh frozen plasma is used in burn resuscitation as a colloid to reduce crystalloid volumes, as a plasma-inclusive adjunct targeting endotheliopathy, and historically as the primary colloid in…
- Pediatric burn fluid resuscitationin editorial review
- Abdominal compartment syndrome in burn resuscitation
Abdominal compartment syndrome (ACS) is a sustained intra-abdominal pressure above 20 mmHg with new organ dysfunction, arising in severely burned patients as a secondary complication of large-volume…
- Hemodynamic monitoring resuscitation endpointsin editorial review